Madworld, a psychological sci-fi horror with paranormal undertones similar to The X-Files and 12 Monkeys, is about Matt Harper, who undergoes top-secret drug trials that allows the subject access to Madworld.  Madworld is a dimensional plane that is the holding area for lost minds, and the government wants to see if Madworld is viable for psychic assassination, and a means to locate high priority enemies of the state.

As Matt continues with the trials, he explores Madworld and confronts malevolent entities, psyches of people from his past, and an environment laden with warp portals and unforeseen dangers.  While in Madworld, Matt discovers the cause and origin of madness--aliens from other dimensions enter the minds of the insane to do unspeakable acts.  He has learned the key to end madness, but the government forces him into completeing objectives such as locating the psyches of known terrorists for psychic assassination.  In the Realworld, Matt becomes unstable and progressively more psychotic.  Matt races to put an end to madness, as he sinks deeper into insanity himself.