Minh Han was born in Saigon, Vietnam. When the Communists took over the country, he and his family fled to the U.S. Dr. Han grew up in Houston, completing his bachelor's and doctorate at Rice University and Baylor College of Medicine, respectively.

During medical school, Dr. Han fell in love with primary care and international medical mission work and chose to pursue the field of family medicine. He then did three years of residency in Roanoke, Virginia, during which time he also served as a county medical examiner.